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Lab Test and investigations

  • normal CBC, ESR, CRP
  • ANA and RF (-)ve

Radiology

  1. Joint space narrowing
  2. Osteophytes
  3. Dense subchondral bones
  4. subchondral cyst

Treatment

The goal of treatment is minimize pain and increase the quality of life. Presently no treatment completely cure the disease.

non-pharmacotherapy

  • Avoiding activities that overload the joints
  • moderate exercise: improve the strength of the muscle that connected to the joints (physiotherapy)
  • weight loss

pharmacotherapy

  • Acetaminophen, NSAID, COX-2 inhibitor (celexicob) *not for long term treatment
  • Intra articular injections: corticosteroid, hyaluronic acid (Hyaluronan)
  • Topical: NSAID (Diclofenac), Capasaicin cream

surgical treatment

  • Joint replacement
  • osteotomy

Herbeden nodes in Osteo arthritis

Herbeden nodes in Osteo arthritis

Mnemonic L: loss of joint space O: osteophytes S: subchondral cysts S: subchondral sclerosis

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