Etiology of Reactive arthritis

Following an infection of Gastro Intestinal or Genito Urinary tract triggers the onset of the disease.

• GI Tract: Shigella, Salmonella, Yersinia, Campylobactor
• GU Tract: Chalmydia trachomatis, Mycoplasma genitalium

Most of the patients are associated with HLA-B27

Antigens from the pathogens are present in synovial fluid.